Evaluating CTO in patients with advanced and treatment-resistant cancers

Advancing Through Clinical Innovation

Tactical Therapeutics is actively advancing clinical development of its lead therapy, CTO (Carboxyamidotriazole Orotate), through studies focused on safety, efficacy, and real-world impact in patients with limited treatment options.

Our clinical program is designed to validate a new approach to targeting cancer resistance.

Current Focus

Focused on High-Unmet-Need Patients

Our clinical trials primarily focus on patients with advanced and recurrent cancers, including glioblastoma, where standard therapies have failed or provide limited benefit.

By targeting these populations, we aim to deliver meaningful outcomes where the need is greatest.

Clinical Development of CTO

CTO has been evaluated in early-phase clinical trials to assess its safety profile, pharmacokinetics, and therapeutic activity.

Encouraging Early Outcomes

Clinical data to date demonstrate promising activity in patients with advanced solid tumors, newly diagnosed and recurrent glioblastoma (ngbm & rgbm). 

one-year survival rate
93%
two-year survival rate
69%
Complete and partial responses observed
Favorable safety profile

Why It Matters

A New Direction in Clinical Oncology

Traditional Therapies Often Fail

Traditional therapies often fail due to resistance and limited ability to reach tumor sites—especially in the brain. CTO is designed to address both challenges.

By combining multi-pathway targeting with effective delivery, our clinical program represents a potential shift in how aggressive cancers are treated.

Future Development

Expanding Clinical Opportunities

Tactical Therapeutics is preparing for the next stages of clinical development, including expanded trials and broader applications across additional solid tumors.

We are actively exploring opportunities to accelerate development through strategic partnerships and collaborations.

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